研究者総覧 - 下田　恵

シモダ　ケイ
下田　恵

所属大分大学医学部基礎医学・医化学

職種准教授

論文
論文	Biocatalytic Ability of the Hairy Bracket Mushroom (Trametes hirsuta): Bio-reduction of Carbonyl Compounds International Journal of Current Microbiology and Applied Sciences 15 (1),40-47頁 2026/01/10
論文	Preparation of Paclitaxel-Anionic Nanoparticles, Memantine (Memary) Gluco-oligosaccharides, α-Tocopherol Glycoside, Daidzein Glycoside, and Glycitein Glycoside and Their Application for Treatment of Skin Cancer, Dementia, Parkinson's Disease, and Allergy International Journal of Current Microbiology and Applied Sciences 14 (11),157-168頁 2025/11
論文	Preparation of Paclitaxel Glycoside-Anionic Nanoparticles, Curcumin Gluco-oligosaccharides, α-Tocopherol Glycoside, Daidzein Glycoside, and Genistein Glycoside and their Application for Treatment of Skin Cancer, Dementia, and Allergy International Journal of Current Microbiology and Applied Sciences 13 (7),137-147頁 2024/07/10
論文	Biocatalytic Preparation of Chiral Hydroxy Esters using Entomogenous Fungi: Bio-reduction of Keto Esters by Tochukaso and Related Species International Journal of Current Microbiology and Applied Sciences 13 (6),155-163頁 2024/06/10
論文	Transdermal Delivery of Paclitaxel-Anionic Nanoparticles to Epidermis Layer, Pterostilbene, and Pterostilbene glycoside, and Their Application for Treatment of Skin Cancer and Wrinkle International Journal of Current Microbiology and Applied Sciences 13 (4),1-7頁 2024/04/10
論文	Transdermal Delivery of Anionic Nanoparticles of Resveratrol, Cannabidiol, Paclitaxel and Paclitaxel Glucoside to Epidermis and their Application for Treatment of Skin Cancer International Journal of Current Microbiology and Applied Sciences 13 (3),125-132頁 2024/03/10
論文	Enzymatic Synthesis of Memantine (Memary) Oligosaccharides (Gluco-oligosaccharides) and their application as anti-dementia drugs that cross the Blood-Brain Barrier (BBB) International Journal of Current Microbiology and Applied Sciences 12 (8),1-6頁 2023/08/10
論文	Dispersion of Cannabidiol Into Small-Sized Nanoparticles Using Technol PG NATURAL PRODUCT COMMUNICATIONS 17 (10),1-3頁 2022/10
論文	Enzymatic Synthesis of Resveratrol Oligosaccharides (Gluco-oligosaccharides) and their Enhanced Application as Antidementia Drugs that Cross the Blood-brain Barrier (BBB) International Journal of Current Microbiology and Applied Sciences 11 (7),260-266頁 2022/07/10
論文	Effect of Magnesium Ion on the Radical-Scavenging Rate of Pterostilbene in an Aprotic Medium: Mechanistic Insight into the Antioxidative Reaction of Pterostilbene Antioxidants 11 (2),340-340頁 2022/02/09
論文	Synthesis of Ester-Linked Paclitaxel-Glycoside Conjugate as a Water-Soluble Paclitaxel Derivative—Maltoside Modification of Paclitaxel through Ester-Linker (Ester-Spacer) Natural Product Communications 16 (9) 2021/09/06
論文	Synthesis of Ester-Linked Paclitaxel–Glycoside Conjugate and Its Drug Delivery System Using Hybrid-Bio-Nanocapsules Targeted With Trastuzumab Natural Product Communications 16 (1) 2021/01/29
論文	Regioselective hydroxylation and dehydrogenation of capsaicin and dihydrocapsaicin by cultured cells of Phytolacca americana Bioscience, biotechnology, and biochemistry 85 (1),103-107頁 2021/01/07
論文	Curcumin Oligosaccharides (Gluco-oligosaccharides) Penetrate the Blood-Brain Barrier in Mouse Brain: Glycoside (Polysaccharide) Modification Approach for Brain Drug Delivery Across the Blood-Brain Barrier and Tumor Drug Delivery Natural Product Communications 15 (11) 2020/11/01
論文	Water-Soluble Glycosylated Resveratrol for Measuring Residual Dipolar Coupling in NMR NATURAL PRODUCT COMMUNICATIONS 15 (8) 2020/08
論文	Relationship between the radical-scavenging activity of selected flavonols and thermodynamic parameters calculated by density functional theory. Free radical research 54 (7),535-539頁 2020/07
論文	Glycosylation of stilbene compounds by cultured plant cells Molecules 25 (6) 2020
論文	Stereoselective Reduction of Bisdemethoxycurcumin to (R)-Hexahydrobisdemethoxycurcumin by Cultured Morus bombycis Plant Cells Natural Product Communications 15 (3) 2020
論文	Transdermal Delivery of Small-Sized Resveratrol Nanoparticles to Epidermis Using Anionic Phospholipids Natural Product Communications 15 (9) 2020
論文	Production of Tetrahydrocurcumin From Curcumin by Cultured Plant Cells and Inhibitory Effects of Curcuminoids on NF-kappa B Activity NATURAL PRODUCT COMMUNICATIONS 14 (9) 2019/09
論文	Chemo-enzymatic Synthesis of Ester-Linked Docetaxel-Glycoside Conjugate and its Drug Delivery System Using Hybrid-Bio-Nanocapsules Targeted With Trastuzumab and Cetuximab Natural Product Communications 14 (6) 2019/06/26
論文	Application of Racemization Process to Dynamic Resolution of (RS)-Phenylephrine to (R)-Phenylephrine beta-D-Glucoside by Nicotiana tabacum Glucosyltransferase NATURAL PRODUCT COMMUNICATIONS 13 (11),1465-1466頁 2018/11
論文	Synthesis of Ester-linked Taxol-oligosaccharide Conjugate and Its Drug Delivery System Using Bio-nanocapsules and Hybrid-bio-nanocapsules NATURAL PRODUCT COMMUNICATIONS 13 (8),933-934頁 2018/08
論文	Synthesis of Ester-linked Taxol-glycoside Conjugate and Its Application to Drug Delivery System Using Immunoliposome Targeted with Trastuzumab and Cetuximab NATURAL PRODUCT COMMUNICATIONS 13 (7),807-808頁 2018/07
論文	Resveratrol Oligosaccharide Induces mRNA Expression for SIRT NATURAL PRODUCT COMMUNICATIONS 13 (4),455-456頁 2018/04
論文	Ferulic Acid, Methyl Ferulate, and Ferulic Acid Glucopyranosyl Ester Isolated from Cultured Cells of Phytolacca americana NATURAL PRODUCT COMMUNICATIONS 13 (1),67-68頁 2018/01
論文	Biotransformation of Daidzein to Diadzein-7-Glucoside and Its Anti-allergic Activity NATURAL PRODUCT COMMUNICATIONS 12 (11),1741-1742頁 2017/11
論文	Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 81 (2),226-230頁 2017/02
論文	Pterostilbene and its glucoside induce type XVII collagen expression Natural Product Communications 12 (1),85-86頁 2017/01/01
論文	Synthesis of Ester-linked Docetaxel-glycoside Conjugate and Its Application to Drug Delivery System using Immunoliposome Targeted with Trastuzumab NATURAL PRODUCT COMMUNICATIONS 11 (11),1635-1636頁 2016/11
論文	Glycosylation of chrysin by cultured cells of eucalyptus perriniana Natural Product Communications 11 (8),1097-1098頁 2016/08/01
論文	Optical Resolution of (RS)-Denopamine to (R)-Denopamine beta-D-Glucoside by Glucosyltransferase from Phytolacca americana Expressed in Recombinant Escherichia coli NATURAL PRODUCT COMMUNICATIONS 11 (8),1121-1122頁 2016/08
論文	Synthesis of epsilon-Viniferin Glycosides by Glucosyltransferase from Phytolacca americana and their Inhibitory Activity on Histamine Release from Rat Peritoneal Mast Cells NATURAL PRODUCT COMMUNICATIONS 10 (6),1017-1018頁 2015/06
論文	Synthesis of Resveratrol Glycosides by Plant Glucosyltransferase and Cyclodextrin Glucanotransferase and Their Neuroprotective Activity NATURAL PRODUCT COMMUNICATIONS 10 (6),995-+頁 2015/06
論文	Regioselective Glycosylation of 3-, 5-, 6-, and 7-Hydroxyflavones by Cultured Plant Cells Natural Product Communications 10 (6) 2015
論文	Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol by glucosyltransferase from P. americana expressed in Bacillus subtilis and their chemopreventive activity against cancer, allergic, and Alzheimer’s diseases Glycobiology Insights 4,1-6頁 2014/01
論文	Regioselective Hydroxylation and Glucosylation of Flavanones with Cultured Plant Cells of Eucalyptus perriniana NATURAL PRODUCT COMMUNICATIONS 8 (7),905-906頁 2013/07
論文	Synthesis of Resveratrol Glycosides by Cultured Plant Cells NATURAL PRODUCT COMMUNICATIONS 8 (7),907-909頁 2013/07
論文	Chemo-enzymatic Synthesis of Propionyl-ester-linked Taxol-monosaccharide Conjugate and its Drug Delivery System Using Hybrid-Bio-nanocapsules Targeting Brain Glioma Cells. Clinical medicine insights. Women's health 6,71-5頁 2013
論文	Regioselective hydroxylation and glucosylation of α- And β-pinenes with cultured cells of eucalyptus perriniana Natural Product Communications 8 (7),847-849頁 2013
論文	Glycosylation of Vanillin and 8-Nordihydrocapsaicin by Cultured Eucalyptus perriniana Cells MOLECULES 17 (5),5013-5020頁 2012/05
論文	Regioselective formation of silybin-23-β-D-glucoside by glucosylation of silybin with cultured plant cells of Eucalyptus perriniana Natural Product Communications 7 (4),531-532頁 2012/04/01
論文	Regioselective glucosidation of trans-resveratrol in Escherichia coli expressing glucosyltransferase from Phytolacca americana BIOTECHNOLOGY LETTERS 34 (3),475-481頁 2012/03
論文	Chemo-enzymatic synthesis of ester-linked 2-phenylindole-3-carboxaldehyde-monosaccharide conjugate as potential prodrug. Biochemistry insights 5,17-20頁 2012
論文	Chemo-enzymatic synthesis of glycolyl-ester-linked taxol-monosaccharide conjugate and its drug delivery system using hepatitis B virus envelope L bio-nanocapsules. Biochemistry insights 5,11-5頁 2012
論文	Synthesis of Xylooligosaccharides of Daidzein and Their Anti-Oxidant and Anti-Allergic Activities INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 12 (9),5616-5625頁 2011/09
論文	Biotransformation of Cinnamic Acid, p-Coumaric Acid, Caffeic Acid, and Ferulic Acid by Plant Cell Cultures of Eucalyptus perriniana Agricultural and Biological Chemistry 74 (9),1920-1924頁 2010/09/23
論文	Synthesis of beta-Maltooligosaccharides of Glycitein and Daidzein and their Anti-Oxidant and Anti-Allergic Activities MOLECULES 15 (8),5153-5161頁 2010/08
論文	Enzymatic synthesis and anti-allergic activities of curcumin oligosaccharides Biochemistry Insights 3,1-5頁 2010/01
論文	The synthesis of bioactive compounds using plant cultured cells -glycosylation- JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 62 (1),112-113頁 2010/01
論文	Bioremediation of Fluorophenols by Glycosylation with Immobilized Marine Microalga Amphidinium Crassum Environmental Health Insights 4 2010
論文	Production of hesperetin glycosides by Xanthomonas campestris and cyclodextrin glucanotransferase and their anti-allergic activities Nutrients 2 (2),171-180頁 2010
論文	Phytoremediation of benzophenone and bisphenol a by glycosylation with immobilized plant cells. Environmental health insights 3,19-25頁 2009/04
論文	Bioremediation of Bisphenol a and Benzophenone by Glycosylation with Immobilized Marine Microalga Pavlova sp Environmental Health Insights 3 2009
論文	Glycosylation of daidzein by the Eucalyptus cell cultures PHYTOCHEMISTRY 69 (12),2303-2306頁 2008/09
論文	High production of β-thujaplicin glycosides by immobilized plant cells of Nicotiana tabacum Acta Biologica Hungarica 59 (3),347-355頁 2008/09
論文	Synthesis of oligosaccharides of genistein and quercetin as potential anti-inflammatory agents CHEMISTRY LETTERS 37 (8),876-877頁 2008/08
論文	Glycosylation of hesperetin by plant cell cultures PHYTOCHEMISTRY 69 (5),1135-1140頁 2008/03
論文	Production of curcumin oligosaccharides by glycosylation with Parthenocissus tricuspidata Japanese Journal of Plant Science 2 (2),43-45頁 2008/02
論文	Glycosylation of tocopherols by cultured cells of Eucalyptus perriniana PHYTOCHEMISTRY 68 (21),2678-2683頁 2007/11
論文	Glucosylation of phenols and phenylalkyl alcohols using cultured plant cells Biotechnology Journal 2 (10),1294-1296頁 2007/10
論文	Biotransformation of raspberry ketone and zingerone by cultured cells of Phytolacca americana PHYTOCHEMISTRY 68 (4),487-492頁 2007/02
論文	Biotransformation of thymol, carvacrol, and eugenol by cultured cells of Eucalyptus perriniana PHYTOCHEMISTRY 67 (20),2256-2261頁 2006/10
論文	Glycosylation of vitamin E homologue by cultured plant cells CHEMISTRY LETTERS 35 (3),324-325頁 2006/03
論文	Biotransformation of monofluorophenols by cultured cells of Eucalyptus perriniana Plant Biotechnology 23 (3),329-331頁 2006
論文	Regioselective hydroxylation, reduction, and glycosylation of diphenyl compounds by cultured plant cells of Eucalyptus perriniana Plant Biotechnology 23 (3),291-296頁 2006
論文	Asymmetric Transformation of Enones with Synechococcus sp. PCC 7942 Bull. Chem. Soc. Jpn. 77 (12),2269-2272頁 2004/12/15
論文	Asymmetric transformation of enol acetates with esterases from Marchantia polymorpha JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 29 (1-6),123-127頁 2004/06
論文	Asymmetric epoxidation of digeranyl by cultured cells of Nicotiana tabacum Journal of Labelled Compounds and Radiopharmaceuticals 46 (5),401-409頁 2003
論文	Purification and characterization of gentisic acid glucosyltransferase from the cultured cells of Catharanthus roseus JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 17 (2),59-63頁 2002/04
論文	Biotransformation of phenolic compounds by the cultured cells of Catharanthus roseus JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 16 (5-6),275-281頁 2002/02
論文	Isolation and characterization of UDP-glucosyltransferase in the cultured cells of Nicotiana tabacum HETEROCYCLES 56 (1-2),509-514頁 2002/01
論文	A novel reductase participating in the hydrogenation of an exocyclic C-C double bond of enones from Nicotiana tabacum Bulletin of the Chemical Society of Japan 75 (4),813-816頁 2002
論文	Diastereoselective formation of disaccharides from (RS)-1-phenylethanol by cultured cells of Catharanthus roseus Bulletin of the Chemical Society of Japan 74,539-542頁 2001/01/01
論文	A 38 kDa allylic alcohol dehydrogenase from the cultured cells of Nicotiana tabacum Phytochemistry 55 (4),297-303頁 2000/11/24
論文	Biotransformation of hydroxycoumarins by the cultured cells of Nicotiana tabacum JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 10 (5),477-481頁 2000/10
論文	Biotransformation of enones with biocatalysts - two enone reductases from Astasia longa JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 8 (4-6),255-264頁 2000/02
論文	Asymmetric hydrogenation of the C-C double bond of enones with the reductases from Nicotiana tabacum Chemistry Letters (8),850-851頁 2000
論文	Cloning of cDNA encoding ethylene-responsive element binding protein-5 in the cultured cells of Nicotiana tabacum Mitochondrial DNA 11 (1-2),125-129頁 2000
論文	Facile syntheses of [8,9-2H2]- and [8-2H]-digeranyl Journal of Labelled Compounds and Radiopharmaceuticals 43 (13),1301-1309頁 2000
論文	Asymmetric hydrolysis of enol esters with two esterases from Marchantia polymorpha Tetrahedron Asymmetry 11 (5),1063-1066頁 1999/03/24
論文	Glucosylation of benzyl alcohols by the cultured suspension cells of Nicotiana tabacum and Catharanthus roseus JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 6 (1-2),67-73頁 1999/01
論文	Asymmetric hydrolysis of enol acetates with the cultured cells of Marchantia polymorpha JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 5 (1-4),143-147頁 1998/09
論文	Stereochemistry in the reduction of enones by the reductase from Euglena gracilis Z PHYTOCHEMISTRY 49 (1),49-53頁 1998/09
論文	Asymmetric hydrolysis of alpha-alkylated cyclohexanone enol acetates by the cultured cells of Marchantia polymorpha TETRAHEDRON-ASYMMETRY 8 (16),2671-2673頁 1997/08
論文	A facile synthesis of (S-) and (R)-[6-H-2]carvones and (S)- and (R)-[2-H-2]limonenes JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 39 (4),285-290頁 1997/04
論文	Novel reductase participation in the syn-addition of hydrogen to the C=C bond of enones in the cultured cells of Nicotiana tabacum JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (4),355-358頁 1996/02
論文	Introduction of oxygenated functional groups into 3-carene and 2-pinene by cultured cells Phytochemistry 37 (2),401-403頁 1994
論文	Stereochemistry in the reduction of the C=C bond of verbenone with a reductase from the cultured cells of Nicotiana tabacum Journal of the Chemical Society, Chemical Communications (18),1426-1427頁 1993