研究者総覧
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イマイ ヒロミツ
今井 浩光
所属
大分大学 医学部 基礎医学・医療倫理学
職種
教授
論文
論文
Water intake during drinking does not alleviate hangover symptoms. Frontiers in pharmacology 17,1852528-1852528頁 2026/06
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Fixed Versus Lottery Incentives for Promoting Engagement With a Cadence-Based Smartphone App: Randomized Crossover Trial JMIR Formative Research 10,e86189-e86189頁 2026/05/27
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Utility of Modeling and Simulations in Drug Development: Contrasting Japan, US and UK Descriptions of PBPK Modeling from Package Inserts. The AAPS journal 28 (2),60-60頁 2026/02/10
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Cadence-Based Pedometer App With Financial Incentives to Enhance Moderate-to-Vigorous Physical Activity: Development and Single-Arm Feasibility Study. JMIR formative research 8,e56376 2024/10/24
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Effects of rifampicin on the pharmacokinetics and safety of carotegrast methyl in healthy subjects: A randomized 2 × 2 crossover study. British journal of clinical pharmacology 90 (6),1395-1407頁 2024/06
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Evaluation of the potential drug-drug interactions of carotegrast methyl with midazolam, prednisolone or atorvastatin in healthy adults. British journal of clinical pharmacology 90 (3),871-881頁 2024/03
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臨床薬理学教育においてポリファーマシーに関する症例シナリオを導入した医療面接実習の有用性 学生及び教員の双方向からの検討 日本臨床薬理学会学術総会抄録集 45回,np283-np284頁 2024
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大分大学医学部附属病院で実施した臨床倫理コンサルテーションの評価研究 大分県医学会雑誌 30,65-69頁 2023/10
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Association between psychomotor function and ALDH2 genotype after consuming barley shochu: A randomized crossover trial. Clinical and translational science 16 (4),686-693頁 2023/02/07
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Creating an in vivo hypoxic environment by gas inhalation for the potential evaluation of new pulse oximeters Translational and Regulatory Sciences 5 (1),23-27頁 2023/02
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Pharmacokinetics of lanoconazole in human skin after repeated topical application The Journal of Dermatology 2022/07/10
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A Phase 1 Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Respiratory Syncytial Virus (RSV) Neutralizing Monoclonal Antibody MK-1654 in Healthy Japanese Adults. Clinical and translational science 15 (7),1753-1763頁 2022/05/03
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Scientific misconduct in sponsored clinical trials in Japan: published cases are the “tip of the iceberg” Translational and Regulatory Sciences 4 (2),30-36頁 2022
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PBPK MODEL FOR CAMOSTAT, A REPURPOSED TMPRSS2 INHIBITOR, PREDICTS THE OPTIMAL DOSE FOR THE TREATMENT OF COVID-19 Clinical Pharmacology & Therapeutics 2021
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The μ-opioid receptor gene polymorphism 118A>G weakens the pharmacological action of buprenorphine. International journal of clinical pharmacology and therapeutics 58 (11),626-633頁 2020/11
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Development of a simultaneous quantitation for short-, medium-, long-, and very long-chain fatty acids in human plasma by 2-nitrophenylhydrazine-derivatization and liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 1126-1127,121771-121771頁 2019/09/15
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No Effect of Digoxin on Rosuvastatin Pharmacokinetics in Healthy Subjects: Utility of Oita Combination for Clinical Drug-Drug Interaction Study. Clinical and translational science 12 (5),513-518頁 2019/09
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Histological evaluation of nintedanib in non-alcoholic steatohepatitis mice. Life sciences 228,251-257頁 2019/07/01
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ゲフィチニブ錠250mg「サワイ」の健康成人における生物学的同等性試験 新薬と臨牀 68 (5),624-637頁 2019/05
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The Pharmacokinetic Exposure to Fexofenadine is Volume-Dependently Reduced in Healthy Subjects Following Oral Administration With Apple Juice. Clinical and translational science 9 (4),201-6頁 2016/08
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An Assessment of the Oral Bioavailability of Three Ca-Channel Blockers Using a Cassette-Microdose Study: A New Strategy for Streamlining Oral Drug Development. Journal of pharmaceutical sciences 104 (9),3154-61頁 2015/09
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Plasma capric acid concentrations in healthy subjects determined by high-performance liquid chromatography. Annals of clinical biochemistry 52 (Pt 5),588-96頁 2015/09
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Development and validation of high performance liquid chromatographic method for determination of pilocarpine in human plasma. Japanese Journal of Therapeutic Drug Monitoring 32 (3),94-100頁 2015
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The relationship between trichlormethiazide-induced hyperuricemia and the genotypes of uric acid transporters Journal of Pharmacological Sciences 2015
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Determination of domperidone in human plasma using high performance liquid chromatography with fluorescence detection for clinical application. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 961,86-90頁 2014/06/15
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The effect of experimentally induced sleep disturbance on the pharmacokinetics of lorazepam in healthy volunteers. International journal of clinical pharmacology and therapeutics 52 (6),519-24頁 2014/06
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Pharmacokinetics of teriparatide after subcutaneous administration to volunteers with renal failure: a pilot study. International journal of clinical pharmacology and therapeutics 52 (2),166-74頁 2014/02
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ADVERSE DRUG EVENTS CAUSED BY POTENTIALLY INAPPROPRIATE MEDICATION IN HOME-BOUND ELDERLY PATIENTS BY NATION-WIDE SURVEY Basic & Clinical Pharmacology & Toxicology 2014
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Bose-Einstein condensate on a persistent-supercurrent atom chip Applied Physics B 2014
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ガスクロマトグラフィー-μ electron capture detection(μECD)を用いたトリアゾラム及びミダゾラムの血漿中濃度測定法と薬物動態試験への応用 薬学雑誌 134 (1),119-25頁 2014
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球形吸着炭クレメジンの薬物相互作用 臨床薬理 44 (2),77-84頁 2013/03
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The effect of carboxylesterase 1 (CES1) polymorphisms on the pharmacokinetics of oseltamivir in humans. European journal of clinical pharmacology 69 (1),21-30頁 2013/01
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Effects of dosing interval on the pharmacokinetic and pharmacodynamic interactions between the oral adsorbent AST-120 and triazolam in humans EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 68 (12),1605-1610頁 2012/12
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Clinical pharmacological study of alendronate intravenous infusion (GTH-42V) in postmenopausal women with impaired renal function in Japan Japanese Journal of Clinical Pharmacology and Therapeutics 43 (6),365-373頁 2012/11
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Determination of celiprolol in human plasma using high performance liquid chromatography with fluorescence detection for clinical application. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 904,88-92頁 2012/09/01
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Itraconazole and domperidone: a placebo-controlled drug interaction study. European journal of clinical pharmacology 68 (9),1287-94頁 2012/09
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Collisional loss rates of sodium Bose-Einstein condensates in the
F
=2 state in a one-dimensional optical lattice Physical Review A 2012
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Effect of renal impairment on the pharmacokinetics of memantine. Journal of pharmacological sciences 119 (4),324-9頁 2012
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THE EFFECTS OF
OPRM1
c.118A>G POLYMORPHISM ON THE PHARMACODYAMICS OF BUPRENORPHINE IN HUMANS Clinical Pharmacology & Therapeutics 2012
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Duration of drug interactions: putative time courses after mechanism-based inhibition or induction of CYPs. Expert review of clinical pharmacology 4 (4),409-11頁 2011/07
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The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans. Pharmacogenetics and genomics 21 (2),84-93頁 2011/02
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Dependence of Berry's phase on the sign of the g factor for conical rotation of a magnetic field, measured without any dynamical phase shift Physical Review A 2011
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Optimized evaporative cooling for sodium Bose-Einstein condensation against three-body loss Physical Review A 2011
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Pharmacokinetics and pharmacodynamics of low doses of midazolam administered intravenously and orally to healthy volunteers. Clinical and experimental pharmacology & physiology 37 (3),290-5頁 2010/03
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Effect of renal impairment on the pharmacokinetics of disopyramide and its metabolite and serum insulin level: A single dose study Japanese Journal of Clinical Pharmacology and Therapeutics 41 (1),35-42頁 2010/01
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Benzbromarone pharmacokinetics and pharmacodynamics in different cytochrome P450 2C9 genotypes. Drug metabolism and pharmacokinetics 25 (6),605-10頁 2010
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Measurement of the second-order Zeeman effect on the sodium clock transition in the weak-magnetic-field region using the scalar Aharonov-Bohm phase Physical Review A 2010
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Ramsey Spectroscopy and Geometric Operations on Sodium Bose-Einstein Condensates Using Two-Photon Stimulated Raman Transitions Journal of the Physical Society of Japan 2010
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A Modified Route to Creating Bose-Einstein Condensates of Sodium Atoms Applied Physics Express 2009
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DEMONSTRATION OF ATOM INTERFEROMETER COMPRISED OF GEOMETRIC BEAM SPLITTERS Proceedings of the Symposium Frequency Standards and Metrology 2009
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GEOMETRIC UNIVERSAL SINGLE QUBIT OPERATION OF COLD TWO-LEVEL ATOMS Proceedings of the International Symposium on Foundations of Quantum Mechanics in the Light of New Technology 2009
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Phase shift of an adiabatic rotating magnetic field in Ramsey atom interferometry for m=0 sodium-atom spin states Physical Review A 2009
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The recovery time-course of CYP3A after induction by St John's wort administration. British journal of clinical pharmacology 65 (5),701-7頁 2008/05
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Complete Geometric Universal Single Qubit Operation of Cold Two-Level Atoms Conference on Lasers and Electro-Optics & Quantum Electronics and Laser Science Conference, Vols 1-9 2008
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Demonstration of pure geometric universal single-qubit operation on two-level atoms Physical Review A 2008
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Effect of the treatment period with erythromycin on cytochrome P450 3A activity in humans. Journal of clinical pharmacology 47 (7),871-6頁 2007/07
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Dual magneto-optical trap of sodium atoms in ground hyperfine
F
=1 and
F
=2 states Japanese Journal of Applied Physics 2007
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Influences of CYP2C9 genotype on pharmacokinetics and pharmacodynamics of benzbromarone Clinical Pharmacology & Therapeutics 2006
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Effect of St. John's wort on the pharmacokinetics of theophylline in healthy volunteers. Journal of clinical pharmacology 44 (1),95-101頁 2004/01
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