研究者総覧 - 伊波　英克

イハ　ヒデカツ
伊波　英克

所属大分大学医学部基礎医学・微生物学

職種准教授

論文
論文	Clathrin-associated SCYL2 contributes to the activation of PI3K/AKT signaling and tumorigenesis through PTEN phosphorylation in adult T-cell leukemia/lymphoma. Cancer gene therapy 33 (3),314-322頁 2026/02/16
論文	Complex Role of Regulatory T Cells (Tregs) in the Tumor Microenvironment: Their Molecular Mechanisms and Bidirectional Effects on Cancer Progression. International journal of molecular sciences 25 (13) 2024/07/04
論文	Disulfidptosis: A Novel Prognostic Criterion and Potential Treatment Strategy for Diffuse Large B-Cell Lymphoma (DLBCL). International journal of molecular sciences 25 (13) 2024/06/28
論文	HTLV-1: Neglected Virus in Southeast Asia for Decades Borneo Journal of Medical Sciences (BJMS) 18 (2) 2024/05/19
論文	Proteomic analysis of adult T-cell leukemia/lymphoma: A biomarker identification strategy based on preparation and in-solution digestion methods of total proteins. Leukemia research 138,107454-107454頁 2024/03
論文	Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2low Adult T-Cell Leukemia/Lymphoma. International journal of molecular sciences 25 (5) 2024/02/29
論文	IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectors Frontiers in Oncology 13 2024/01/24
論文	The Novel Link between Gene Expression Profiles of Adult T-Cell Leukemia/Lymphoma Patients' Peripheral Blood Lymphocytes and Ferroptosis Susceptibility. Genes 14 (11) 2023/10/27
論文	c‐FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma Clinical and Translational Medicine 13 (8) 2023/08/15
論文	RAISING is a high-performance method for identifying random transgene integration sites. Communications biology 5 (1),535-535頁 2022/06/02
論文	Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia IJID Regions 2,126-129頁 2022/03
論文	TAS-116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T-cell leukemia. Cancer science 113 (2),684-696頁 2022/02
論文	TAS‐116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T‐cell leukemia Cancer Science 113 (2),684-696頁 2021/11/27
論文	Phylogenetic and evolutionary analyses of the VP4 gene of P[9] rotaviruses Gazi Medical Journal 32 (4 A),638-646頁 2021/11/05
論文	Depletion of TAX1BP1 amplifies innate immune responses during respiratory syncytial virus infection. Journal of virology 95 (22),JVI0091221 2021/08/25
論文	アルカリ性ミネラルウォーターの長期間飲水が及ぼす腸内細菌叢及び体調に与える影響日本医学検査学会抄録集 70回,65-65頁 2021/05
論文	A high-throughput detection method for the clonality of Human T-cell leukemia virus type-1-infected cells in vivo. International journal of hematology 112 (3),300-306頁 2020/07/29
論文	An outbreak of gastroenteritis by emerging norovirus GII.2[P16] in a kindergarten in Kota Kinabalu, Malaysian Borneo. Scientific reports 10 (1),7137-7137頁 2020/04/28
論文	PSK1 coordinates glucose metabolism and utilization and regulates energy-metabolism oscillation in Saccharomyces cerevisiae. Yeast (Chichester, England) 37 (3),261-268頁 2020/03
論文	Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells. Biochimica et biophysica acta. Molecular cell research 1867 (2),118615-118615頁 2020/02
論文	Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7. Leukemia 34 (1),180-195頁 2020/01
論文	Long-Term Potable Effects of Alkalescent Mineral Water on Intestinal Microbiota Shift and Physical Conditioning Evidence-Based Complementary and Alternative Medicine 2019,1-10頁 2019/11/19
論文	The regulation of NDRG2 expression during ATLL development after HTLV-1 infection. Biochimica et biophysica acta. Molecular basis of disease 1865 (10),2633-2646頁 2019/10/01
論文	Long-Term Potable Effects of Alkalescent Mineral Water on Intestinal Microbiota Shift and Physical Conditioning. Evidence-based complementary and alternative medicine : eCAM 2019,2710587-2710587頁 2019
論文	Arginine methylation of HSP90A by protein arginine methyltransferase PRMT5 promotes development of adult T-cell leukemia CANCER SCIENCE 109,737 2018/12
論文	Human-porcine reassortant rotavirus generated by multiple reassortment events in a Sri Lankan child with diarrhea. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 65,170-186頁 2018/11
論文	造血器悪性腫瘍におけるSLAMF7の発現様式とその機序、臨床応用への意義(SLAMF7 expression profiles in hematologic malignancies: an interpretation for clinical significance) 臨床血液 59 (9),1696-1696頁 2018/09
論文	Complete Sequences of the Human T-Cell Leukemia Virus Type 1 Proviral Genomes from Newly Established Adult T-Cell Leukemia Cell Lines in Oita Prefecture, Japan. Genome announcements 6 (25) 2018/06/21
論文	The First Outbreak of Athochthonous Zika Virus in Sabah, Malaysia Borneo. PLoS Currents 6,e00090-18. 2018/05/01
論文	Down-regulation of p47 induces high expression of CADMI via the NF-kappa B pathway in adult T-cell leukemia CANCER SCIENCE 109,198 2018/01
論文	Downregulation of dual-specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomas. Cancer science 109 (1),250-258頁 2018/01
論文	Synthetic lethality of PRMT5 inhibition in NDRG2-deficient adult T-cell leukemia through HSP90A dysfunction CANCER SCIENCE 109,40 2018/01
論文	Increased serum vascular endothelial growth factor is associated with acute viral encephalitis in Bangladeshi children. Scientific reports 7 (1),16181-16181頁 2017/11/23
論文	大腸癌におけるDUSP4発現低下は増殖能・浸潤能に関与する日本癌学会総会記事 76回,P-2033頁 2017/09
論文	食道扁平上皮癌におけるCannabinoid receptor 1の発現亢進は転移と予後に相関する日本病理学会会誌 106 (1),375-376頁 2017/03
論文	Overexpression of cannabinoid receptor 1 in esophageal squamous cell carcinoma is correlated with metastasis to lymph nodes and distant organs, and poor prognosis. Pathology international 67 (2),83-90頁 2017/02
論文	Antiobesity and Anti-Inflammatory Effects of Orally Administered Bonito Extracts on Mice Fed a High-Fat Diet. Evidence-based complementary and alternative medicine : eCAM 2017,9187167-9187167頁 2017
論文	Surveillance of norovirus among children with diarrhea in four major hospitals in Bhutan: Replacement of GII.21 by GII.3 as a dominant genotype. PloS one 12 (9),e0184826 2017
論文	Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells CANCER SCIENCE 107 (12),1919-1928頁 2016/12
論文	Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1. Scientific reports 6,31266-31266頁 2016/08/12
論文	Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. The Journal of pathology 239 (1),97-108頁 2016/05
論文	Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development. Scientific reports 5,12841-12841頁 2015/08/13
論文	SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription. Journal of virology 89 (16),8623-31頁 2015/08
論文	Establishment of new predictive markers for distant recurrence of colorectal cancer using lectin microarray analysis. Cancer medicine 4 (2),293-302頁 2015/02
論文	カツオせんじパウダー(KSP)の長期摂取による肥満抑制効果および安全性の検証日本補完代替医療学会学術集会プログラム・抄録集 17回,52-52頁 2014/11
論文	日田天領水の長期飲用が与える体調への影響の評価日本補完代替医療学会学術集会プログラム・抄録集 17回,55-55頁 2014/11
論文	A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period Retrovirology 11(Suppl 1),P44 2014
論文	ATL治療候補薬剤によるATL細胞内の転写プロファイルの変動(Dynamic gene expression alteration in ATL cells after the addition of newly developed anti-tumor chemicals) 日本癌学会総会記事 72回,489-489頁 2013/10
論文	Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice Blood Cancer Journal 3 (8),e132 2013/08
論文	Commensal microbiota contributes to chronic endocarditis in TAX1BP1 deficient mice. PloS one 8 (9),e73205 2013
論文	Passive carriage of rabies virus by dendritic cells. SpringerPlus 2,419-419頁 2013
論文	臓器特異的自己免疫疾患(標的:神経、脈管) マウスにおいてTAX1BP1欠損は炎症症状と心臓系の機能不全の時間・空間的発生を誘発する(TAX1BP1-deficiency evokes spaciotemporal development of inflammatory symptoms and functional failures in the murine cardiac system) 日本免疫学会総会・学術集会記録 40,227-227頁 2011/11
論文	高感度レクチンアレイを用いた成人T細胞白血病/リンパ腫(ATL)細胞の糖鎖プロファイリング Bio Clin 26 (10),916-919頁 2011/09/10
論文	Transactivation of CCL20 gene by Epstein-Barr virus latent membrane protein 1 (Retraction of vol 132, pg 293, 2006) BRITISH JOURNAL OF HAEMATOLOGY 152 (6),787-787頁 2011/03
論文	Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice. Blood 114 (14),2961-8頁 2009/10/01
論文	Development and evaluation of a rapid neutralizing antibody test for rabies. Journal of virological methods 161 (1),58-62頁 2009/10
論文	Evaluation of a new tumor necrosis factor-alpha-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen. Helicobacter 14 (5),135-43頁 2009/10
論文	1.わが国のがん診療感染症と発がん日本医師会雑誌 138,S34-S35 2009/06/15
論文	Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells Leukemia 23 (11),2090-2101頁 2009
論文	ユズ果皮が持つ抗アレルギー能-大分地区の産学連携事業- 果樹試験研究推進協議会会報誌 12,9-14頁 2009
論文	Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation. The EMBO journal 27 (4),629-41頁 2008/02/20
論文	HTLV-1 Tax-mediated TAK1 activation involves TAB2 adapter protein. Biochemical and biophysical research communications 365 (1),189-94頁 2008/01/04
論文	Helicobacter pylori新規蛋白であるTNFα inducing protein(Tipα)を用いたH.pylori感染マウスに対するワクチン効果についての検討感染症学雑誌 81 (3),340-340頁 2007/05
論文	A water-soluble hsp90 inhibitor 17-DMAG suppresses tax-mediated oncogenic signaling both in vitro and in vivo AIDS RESEARCH AND HUMAN RETROVIRUSES 23 (4),594-595頁 2007/04
論文	The mechanism by which overexpression of Gts1p induces flocculation in a FLO8-inactive strain of the yeast Saccharomyces cerevisiae. FEMS yeast research 6 (6),914-23頁 2006/09
論文	Transactivation of CCL20 gene by Epstein-Barr virus latent membrane protein 1. British journal of haematology 132 (3),293-302頁 2006/02
論文	Evidence for NF-kappaB- and CBP-independent repression of p53's transcriptional activity by human T-cell leukemia virus type 1 Tax in mouse embryo and primary human fibroblasts. Journal of virology 79 (14),9346-50頁 2005/07
論文	Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity. Journal of virology 78 (21),11686-95頁 2004/11
論文	Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling. Oncogene 22 (55),8912-23頁 2003/12/04
論文	Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitors. The Journal of biological chemistry 277 (7),5187-93頁 2002/02/15
論文	Functional correlation between the nuclear localization of Fht1p and its flocculation and heat tolerance activities in budding yeast Saccharomyces cerevisiae JOURNAL OF BIOMEDICAL SCIENCE 8 (5),416-420頁 2001/09
論文	Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappa B activation ONCOGENE 20 (33),4484-4496頁 2001/07
論文	Prevalent loss of mitotic checkpoint function in HTLV-1 transformed cell lines holds implications for use of vinca alkaloids in treatment of ATLs. AIDS RESEARCH AND HUMAN RETROVIRUSES 17,S6-S6頁 2001
論文	Pleiotropic effects of HTLV type 1 tax protein on cellular metabolism: Mitotic checkpoint abrogation and NF-kappa B activation AIDS RESEARCH AND HUMAN RETROVIRUSES 16 (16),1633-1638頁 2000/11
論文	Phosphorylation of the GTS1 gene product of the yeast Saccharomyces cerevisiae and its effect on heat tolerance and flocculation FEMS MICROBIOLOGY LETTERS 187 (2),179-184頁 2000/06
論文	Pleiotropic effect of HTLV-1 Tax on multiple cellular processes: Aneuploidy, DNA damage and transcription LEUKEMIA 14 (3),538-538頁 2000/03
論文	Shuttle-vector system for Saccharomyces cerevisiae designed to produce C-terminal-Myc-tagged fusion proteins BIOTECHNIQUES 25 (6),936-938頁 1998/12
論文	Identification and characterization of a novel trans-membrane protein Gene, pdh1, from Schizosaccharomyces pombe DNA Research 4 (6),393-396頁 1997
論文	The posttranslational modification of C-terminal amino acids of the ras super family proteins. Amino Acids 5,147 1993
論文	PRIMARY STRUCTURE OF THE OLIGO-1,6-GLUCOSIDASE OF BACILLUS-CEREUS ATCC7064 DEDUCED FROM THE NUCLEOTIDE-SEQUENCE OF THE CLONED GENE EUROPEAN JOURNAL OF BIOCHEMISTRY 192 (3),609-620頁 1990/09
論文	CLONING AND EXPRESSION IN ESCHERICHIA-COLI OF AN EXTREMELY THERMOSTABLE OLIGO-1,6-GLUCOSIDASE GENE FROM BACILLUS-THERMOGLUCOSIDASIUS JOURNAL OF BACTERIOLOGY 171 (2),1219-1222頁 1989/02